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What are the implications of IV acetaminophen having 100% bioavailability versus the oral formulation which undergoes first pass hepatic metabolism?

Name: What are the implications of IV acetaminophen having 100% bioavailability versus the oral formulation which undergoes first pass hepatic metabolism?
Uploaded: 2017-09-11T00:00:00+00:00
Description: What are the implications of IV acetaminophen having 100% bioavailability versus the oral formulation which undergoes first pass hepatic metabolism? How does this affect C-max and what are the clinical implications?

Published: September 11, 2017

What are the implications of IV acetaminophen having 100% bioavailability versus the oral formulation which undergoes first pass hepatic metabolism?

What are the implications of IV acetaminophen having 100% bioavailability versus the oral formulation which undergoes first pass hepatic metabolism? How does this affect C-max and what are the clinical implications?

Overview

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Created by

Presenter

Jeff Gadsden, MD

Associate Professor
Duke University School of Medicine
Chief, Division of Orthopaedic, Plastic and Regional Anesthesiology
Duke University Medical Center
Chapel Hill, North Carolina

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