Alparslan Turan, MD

Alparslan Turan, MD
 

Associate Professor
Departments of Outcomes Research and General Anesthesiology
Vice Chair of Education
Cleveland Clinic
Cleveland, Ohio

What have we learned about the relationship between the use of IV acetaminophen as part of multimodal pain management in various surgical settings and reduction of length-of-stay outcomes? Video

What have we learned about the relationship between the use of IV acetaminophen as part of multimodal pain management in various surgical settings and reduction of length-of-stay outcomes?

What have we learned about the relationship between the use of IV acetaminophen as part of multimodal pain management in various surgical settings — bariatric surgery, colorectal surgery, TKR, and THR — and reduction of length-of-stay ...
Alparslan Turan, MD

Alparslan Turan, MD

What observations argue that IV acetaminophen should be a component of multimodal pain management, whereas IV opioids should be "rescue" or "pain breakthrough"-alleviating agents? Video

What observations argue that IV acetaminophen should be a component of multimodal pain management, whereas IV opioids should be "rescue" or "pain breakthrough"-alleviating agents?

What clinical observations argue for the position that IV acetaminophen should be a foundation component of multimodal pain management, whereas IV opioids —which while effective, are also associated with a range of problematic side effects ...
Alparslan Turan, MD

Alparslan Turan, MD

What are the mechanisms of action by which IV acetaminophen exerts pain-relieving properties and how is this different from other agents? What is the approved dosing schedule for this agent? Video

What are the mechanisms of action by which IV acetaminophen exerts pain-relieving properties and how is this different from other agents? What is the approved dosing schedule for this agent?

What are the mechanism(s) of action by which IV acetaminophen exerts its pain-relieving properties and how is this differentiated from other agents? And what is the approved dosing schedule for this agent?
Alparslan Turan, MD

Alparslan Turan, MD

What has been the role of IV acetaminophen in establishing Enhanced Recovery After Surgery (ERAS) protocols across the spectrum of surgical procedures; and what are the objectives of ERAS? Video

What has been the role of IV acetaminophen in establishing Enhanced Recovery After Surgery (ERAS) protocols across the spectrum of surgical procedures; and what are the objectives of ERAS?

What has been the role of IV acetaminophen in establishing Enhanced Recovery After Surgery (ERAS) protocols across the spectrum of surgical procedures; and what are the objectives of the ERAS strategy? Is it part of your multimodal approach ...
Alparslan Turan, MD

Alparslan Turan, MD

Given its efficacy and safety profile, across what range of surgical procedures is IV acetaminophen ideally employed as part of an ERAS strategy in the context of multimodal pain mitigation? Video

Given its efficacy and safety profile, across what range of surgical procedures is IV acetaminophen ideally employed as part of an ERAS strategy in the context of multimodal pain mitigation?

Given its documented efficacy and safety profile, across what range of surgical procedures and perioperative situations is IV acetaminophen ideally employed as part of an ERAS strategy in the context of multimodal pain mitigation? What ...
Alparslan Turan, MD

Alparslan Turan, MD

What are the unique advantages -- in the immediate and extended post-operative period -- of IV acetaminophen in the bariatric surgery population? How does this agent offer particular advantages in light of the GI and respiratory disturbances encountered in this patient population? Video

What are the unique advantages -- in the immediate and extended post-operative period -- of IV acetaminophen in the bariatric surgery population? How does this agent offer particular advantages in light of the GI and respiratory disturbances encountered in this patient population?

What are the unique advantages — in the immediate and extended post-operative period — of IV acetaminophen in the bariatric surgery population? How does this agent offer particular advantages in light of the GI and respiratory disturbances ...
Alparslan Turan, MD

Alparslan Turan, MD

Length-of-stay is a critical cost- and best practice metric. What have studies shown as far as the effect of IV acetaminophen on LOS and ERAS across surgical procedures? Video

Length-of-stay is a critical cost- and best practice metric. What have studies shown as far as the effect of IV acetaminophen on LOS and ERAS across surgical procedures?

As you know, length-of-stay (LOS) is a critical cost- and best practice metric reflecting quality of care. In light of this, what have the studies shown as far as the effect of IV acetaminophen on LOS and ERAS benchmarks across the range ...
Alparslan Turan, MD

Alparslan Turan, MD

What is the optimal time for initiating IV acetaminophen? At the beginning of surgery? Before the surgical insult? What is the rationale for pre-emptive use of this pain reliever? Video

What is the optimal time for initiating IV acetaminophen? At the beginning of surgery? Before the surgical insult? What is the rationale for pre-emptive use of this pain reliever?

What is the optimal time for initiating IV acetaminophen? At the beginning of surgery? Before the surgical insult? What is the rationale for pre-emptive use of this pain reliever?
Alparslan Turan, MD

Alparslan Turan, MD

Given the side effects of IV opioids, what role does IV acetaminophen play in reducing opioid doses required to achieve multimodal pain control and ERAS? Video

Given the side effects of IV opioids, what role does IV acetaminophen play in reducing opioid doses required to achieve multimodal pain control and ERAS?

Given the known and problematic side effects of IV opioids — respiratory depression, nausea, vomiting, decreased oxygen saturation, and other effects on GI motility and absorption — what role does IV acetaminophen play in reducing opioid ...
Alparslan Turan, MD

Alparslan Turan, MD

Other non-opioid IV agents that have been explored as co-therapies to achieve ERAS. Does IV acetaminophen have properties that are superior to other agents in the multimodal perioperative context? Video

Other non-opioid IV agents that have been explored as co-therapies to achieve ERAS. Does IV acetaminophen have properties that are superior to other agents in the multimodal perioperative context?

Given the existence of other non-opioid IV agents that have been explored as co-therapies to achieve ERAS, why do you believe IV acetaminophen may have properties — efficacy, safety profile and MOA — that are superior to other agents in ...
Alparslan Turan, MD

Alparslan Turan, MD

What is the rationale for using the IV form of acetaminophen for ERAS and other dimensions of pain control in the operative and post-operative setting? Video

What is the rationale for using the IV form of acetaminophen for ERAS and other dimensions of pain control in the operative and post-operative setting?

Given that opioids are known to inhibit peristalsis and GI absorption and potentially affect PK/PD profiles of oral acetaminophen and other agents, what is the rationale for using the IV form of acetaminophen for ERAS and other dimensions ...
Alparslan Turan, MD

Alparslan Turan, MD

While improvements in LOS are documented with IV acetaminophen, what other improvements and outcomes have been observed in orthopedic, colorectal, and general surgery studies? Video

While improvements in LOS are documented with IV acetaminophen, what other improvements and outcomes have been observed in orthopedic, colorectal, and general surgery studies?

While improvements in LOS are well documented with IV acetaminophen, what other global functional improvements and outcomes — ambulation, in particular — have been observed in orthopedic, colorectal, and general surgery studies evaluating ...
Alparslan Turan, MD

Alparslan Turan, MD

Can you summarize the foundational role of IV acetaminophen in improving functional, pain, and LOS-related outcomes across the spectrum of surgical procedures? Video

Can you summarize the foundational role of IV acetaminophen in improving functional, pain, and LOS-related outcomes across the spectrum of surgical procedures?

Can you summarize the foundational role of IV acetaminophen in improving functional, pain, and LOS-related outcomes across the spectrum of surgical procedures, and therefore, its use as an effective and safe pillar agent that reduces opioid ...
Alparslan Turan, MD

Alparslan Turan, MD