Which of the four classes of genomic alterations--base substitutions, insertions and deletions, copy number alterations, and rearrangements--can a typical multi-gene

Which of the four classes of genomic alterations--base substitutions, insertions and deletions, copy number alterations, and rearrangements--can a typical multi-gene "Hot Spot" test detect?

Which of the four classes of genomic alterations—base substitutions, insertions and deletions, copy number alterations, and rearrangements can a typical multi-gene “Hot Spot” test detect? Which alterations does it fail to detect and why is NGS preferable?


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Presenter

Samuel Klempner, MD

Samuel Klempner, MD

Director of Precision Medicine
The Angeles Clinic and Research Institute
Cedars-Sinai Medical Center
Los Angeles, CA