What is the precise immunopathobiologic mechanism of action (MoA) for agents targeting IL-6 in the setting of RA? How does IL-6 affect bone loss in RA?

What is the precise immunopathobiologic mechanism of action (MoA) for agents targeting IL-6 in the setting of RA? How does IL-6 affect bone loss in RA?

What is the precise immunopathobiologic mechanism of action (MoA) for agents targeting IL-6 in the setting of RA? How does IL-6 affect bone loss in RA?


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Presenter

Leonard Calabrese, DO

Leonard Calabrese, DO

Professor of Medicine
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
R.J. Fasenmyer Chair of Clinical Immunology
Vice Chairman Department of Rheumatic and Immunologic Diseases
Orthopaedic and Rheumatologic Institute