Can you discuss the unique mechanistic effects of IL-6 inhibition -- including the role of GP 130 -- that differentiate it from other cytokines that are targeted in RA?

Can you discuss the unique mechanistic effects of IL-6 inhibition -- including the role of GP 130 -- that differentiate it from other cytokines that are targeted in RA?

Can you discuss the unique mechanistic effects of IL-6 inhibition — including the role of GP 130 — that differentiate it from other cytokines that are targeted in RA? Can its signaling properties be transmitted to sites distal from inflammation?


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CMEducation Resources IQ&A Interactive Intelligence Zone

Presenter

Ernest Choy, MD, FRCP

Ernest Choy, MD, FRCP

Head of Rheumatology and Translational Research
Institute of Infection and Immunity
Director of Arthritis Research UK CREATE Centre and
Welsh Arthritis Research Network (WARN) Cardiff University School of Medicine
Cardiff, United Kingdom