Yvonne Sherrer, MD

Yvonne Sherrer, MD
 

Medical Director/Director of Clinical Research
Centre for Rheumatology, Immunology and Arthritis
Fort Lauderdale, FL


What triggers do you use in your RA patients to begin a DMARD or biologic agent?

What triggers do you use in your RA patients to begin a DMARD or biologic agent?

Under what circumstances do you use monotherapy with methotrexate and when do you use combination therapy and intensify treatment with a biologic agent?

Under what circumstances do you use monotherapy with methotrexate and when do you use combination therapy and intensify treatment with a biologic agent?

What side effects are you most concerned about when using TNFIs or IL-6 inhibitors?

What side effects are you most concerned about when using TNFIs or IL-6 inhibitors?

Have advantages been documented for IL-6 inhibitors that are fully human such as sarilumab?

Have advantages been documented for IL-6 inhibitors that are fully human such as sarilumab?

How good are the disease outcome metrics recommended by ACR and what are their limitations?

How good are the disease outcome metrics recommended by ACR and what are their limitations?

When a suboptimal clinical response is encountered with TNF or interleukins antagonists, what other strategies may be effective? How might an IL-6 inhibitor fit into the treatment plan?

When a suboptimal clinical response has been encountered with TNF or interleukins antagonists, what other biologic strategies have been shown to be effective in clinical trials? How are these sequencing decisions made and where might an ...

Is there a "one-sequence-fits-all" strategy? Or can one start with any of the biologic agents as an initial therapy in conjunction with methotrexate?

Is there a “one-sequence-fits-all” strategy? Or can one start with any of the biologic agents as an initial therapy in conjunction with methotrexate?

And how do you approach the biologically naive patient?

And how do you approach the biologically naïve patient?

What do studies and guidelines suggest as successful therapeutic strategies for RA patients who have been inadequate responders to TNF therapy?

What do studies and guidelines suggest as successful therapeutic strategies for RA patients who have been inadequate responders to TNF therapy? On the basis of what criteria is the decision made to switch to an Il-6 inhibitor or an agent ...

What are the strengths and weaknesses of conventional measures of RA disease activity (i.e., ACR scores) as compared to the increasingly important patient-reported outcomes (PROS)?

What are the strengths and weaknesses of conventional measures of RA disease activity (i.e., ACR scores) as compared to the increasingly important patient-reported outcomes (PROS) that are being used in clinical trials?

What do you think are some of the most important unmet needs in RA?

What do you think are some of the most important unmet needs in RA?