Intended Audience

This complimentary CME educational activity is designed for all cardiology-focused physicians, nurses, NPs, academicians, pharmacists, researchers, investigators, and program directors managing, referring, and/or consulting on patients with atrial fibrillation, with a focus on stroke prevention. We welcome neurology-focused clinicians with a medical and educational needs in the fields of general cardiology, and other providers that are part of the multidisciplinary team caring for patients with these and related conditions, including:

Program Medium

Internet-based program

Method of Physician Participation Utilized in Learning Process

There are no fees for participating and receiving CME credit for this activity. During the period December 22, 2010 through December 22, 2012 participants must 1) read the learning objectives and faculty disclosures; 2) study the educational activity, and are expected to view all 94 segments to successfully complete the activity and earn CME credit; 3) register and complete the evaluation form; and 4) print out CME certificate. REPLACE

Estimated Time to Complete Educational Activity

4.0 hours

Course Overview

In this web-based program, physicians will learn how recent advances in basic and clinical research have helped to advance the understanding of treatment advances in stroke prevention in the setting of atrial fibrillation.

Release Date

December 22, 2010

Expiration Date

December 22, 2012


Participation in this iQ&A interactive Medical Intelligence Zone for Stroke Prevention in Atrial Fibrillation is complimentary, and clinicians are invited to view this CME-certified program and/or share this invitation with other colleagues, departmental staff members, and healthcare professionals.

Grantor Support

Supported by an educational grant from Ortho-McNeil Inc, Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc., administered by Ortho-McNeil Janssen Scientific Affairs, LLC.
Accreditation Statement

This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of The University of Massachusetts Medical School, Office of CME and CMEducation Resources, LLC. The University of Massachusetts Medical School is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation Statement

The University of Massachusetts Medical School designates this enduring material for a maximum of 4.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only credit commensurate with the extent of their participation in the activity.

Policy on Faculty & Provider Disclosure

It is the policy of the University of Massachusetts Medical School to ensure fair balance, independence, objectivity and scientific rigor in all activities. All faculty participating in CME activities sponsored by the University of Massachusetts Medical School are required to present evidence-based data, identify and reference off-label product use and disclose all relevant financial relationships with those supporting the activity or others whose products or services are discussed. Faculty disclosure will be provided in the activity materials.

Program Faculty and Disclosure

Samuel Z. Goldhaber, MD
Program Chairman and Moderator
Professor of Medicine
Harvard Medical School
Director, VTE Research Group
Cardiovascular Division
Brigham and Women's Hospital
President, North American Thrombosis Forum (NATF)
Boston, Massachusetts

Advisor or consultant: Boehringer Ingelheim Pharmaceuticals, Inc., Bristol-Myers Squibb, Eisai, and sanofi-aventis.
Research support: Boehringer Ingelheim Pharmaceuticals, Bristol-Myers Squibb, Eisai, Johnson & Johnson Pharmaceutical Research & Development and sanofi-aventis
Richard C. Becker, MD
Professor of Medicine
School of Medicine
Duke University
Director, Duke Cardiovascular Thrombosis Center
Duke Clinical Research Institute
Durham, North Carolina USA

Grant/Research Support: Johnson & Johnson, Bristol-Myers Squibb, Bayer, Merck, Regado Biosciences

Deepak L. Bhatt, MD, MPH, FACC, FAHA, FSCAI
Chief of Cardiology, VA Boston Healthcare System
Director, Integrated Interventional Cardiovascular Program
Brigham and Women’s Hospital and the VA Boston Healthcare System
Senior Investigator, TIMI Group
Harvard Medical School
Boston, MA

Consultant: Arena, Astra Zeneca, Bristol-Myers Squibb, Cardax, Cogentus, Daiichi Sankyo, Eli Lilly, Eisai, Glaxo Smith Kline, Johnson & Johnson, Medtronic, Millennium, Otsuka, Paringenix, PDL, Philips, Portola, sanofi-aventis, Schering Plough, Takeda, The Medicines Company, Vertex.
Principal Investigator for several potentially related studies. His institution has received funding from Bristol Myers Squibb, Eisai, Ethicon, Heartscape, sanofi-aventis, The Medicines Company

Michael D. Ezekowitz, MD, PhD
Professor and Vice President
Lankenau Institute for Medical Research
Vice President
Clinical Research
Main Line Hospitals
Wynnewood, Pennsylvania

Advisor or Consultant: Boehringer Ingelheim Pharmaceuticals, Inc.; ARYx Therapeutic; Pfizer Inc.; sanofi-aventis; Bristol-Myers Squibb Company; Portola Pharmaceuticals, Inc.; AstraZeneca Pharmaceuticals LP; Daiichi Sankyo, Inc.; Medtronic, Inc.
Grants/Research Support: Boehringer Ingelheim Pharmaceuticals, Inc.; ARYx Therapeutic; Portola Pharmaceuticals, Inc.; Daiichi Sankyo, Inc.

John Fanikos, RPh, MBA
Director of Pharmacy Business and Financial Services
Brigham and Women’s Hospital
Adjunct Clinical Professor of Pharmacy
Northeastern University
Massachusetts College of Pharmacy
Boston, MA

Consulting: Eisai, GlaxoSmithKline, sanofi-aventis

Valentin Fuster, MD, PhD
Director, Mount Sinai Heart
Director, Zena and Michael Wiener Cardiovascular Institute and the Marie-Josée and Henry R Kravis Center of Cardiovascular Health
Richard Gorlin MD Heart Research Foundation Professor of Cardiology at Mount Sinai Medical Center
New York, NY

Nothing to disclose

David A. Garcia, MD
Associate Professor, Division of General Internal Medicine
University of New Mexico
Co-Director, University of New Mexico Anticoagulation Management Service
President, Anticoagulation Forum
Albuquerque, New Mexico USA

Advisor or consultant for: Bohringer Ingelhim Pharmaceuticals, Inc., Bristol-Myers Squibb Company, ARYx Therapeutics, CSL Behring.
Received grants for clinical research from: Bristol-Myers Squibb Company, ARYx Therapeutics, CSL Behring

Christopher B. Granger, MD
Professor of Medicine
Cardiac Care Unit; Co-Director
Cardiovascular Clinical Trials
Duke University Medical Center
Durham, North Carolina

Advisor or Consultant: AstraZeneca Pharmaceuticals LP; Boehringer Ingelheim Pharmaceuticals, Inc.; Bristol-Myers Squibb Company; GlaxoSmithKline; F. Hoffmann-La Roche Ltd; Novartis Pharmaceuticals Corporation; Otsuka Pharmaceutical Co., Ltd.; sanofi-aventis; The Medicines Company
Grants/Research Support: Astellas Pharma, Inc.; AstraZeneca Pharmaceuticals LP; Boehringer Ingelheim Pharmaceuticals, Inc.; Bristol-Myers Squibb Company; GlaxoSmithKline; Eli Lilly and Company; Medtronic, Inc.; Merck & Co., Inc.; sanofi-aventis; The Medicines Company

Jonathan L. Halperin, MD
Mount Sinai School of Medicine
Director, Clinical Cardiology Service
The Zena and Michael A. Wiener Cardiovascular Institute
The Marie-Josée and Henry R. Kravis Center for Cardiovascular Health
New York, New York

Consultant: Astellas Pharma, U.S., Bayer HealthCare, Biotronik, Inc, Boehringer-Ingelheim, Daiichi-Sankyo Pharma, Johnson & Johnson, Portola Pharmaceuticals, Sanofi-Aventis

Elaine M. Hylek, MD, MPH
Associate Professor of Medicine
Department of Medicine
Boston University Medical Center
Boston, Massachusetts

Advisory Boards: Bristol-Myers Squibb, sanofi-aventis, Boehringer-Ingelheim

Scott Kaatz, DO, MSc, FACP
Clinical Associate Professor of Medicine
Associate Residency Program Director
Department of Medicine
Director, Anticoagulation Clinics
Henry Ford Hospital
Detroit, Michigan

Consulting Fees – Pfizer, Boehringer Ingelheim, Bristol Myers Squibb, Ortho McNeil, Sanofi- Aventis
Contracted Research – Boehringer Ingelheim, Bristol Myers Squibb, Ortho McNeil
Other Speaker Bureau – Sanofi-Aventis

Jon Kobashigawa, MD
Medical Director, UCLA Heart Transplant Program
Co-Chief, Division of Clinical Faculty Medicine
Department of Medicine
UCLA School of Medicine
Los Angeles, CA

Research grants, advisory boards, speaker honoraria: Roche, Novartis, Astellas

Peter Libby, MD, FACC
Chief, Cardiovascular Medicine
Brigham and Women’s Hospital
Mallinckrodt Professor of Medicine
Harvard Medical School
Boston, Massachusetts

Nothing to disclose

Alexander G.G. Turpie, MD
Professor of Medicine
McMaster University
Hamilton, Ontario

Consultant: Bayer, Johnson & Johnson, Pfizer, Astellas
Speaker’s Bureau: GlaxoSmithKline, Bayer Canada

Annabelle Volgman, MD, FACC
Associate Professor of Medicine
Medical Director
Heart Center for Women
Rush University Medical College
Chicago, Illinois

Salary – Rush University Medical Center
Consulting Fees – Quaker Oats Company
Contracted Research – NIH
Other Speakers Bureau – Sanofi-Aventis, Forest, Abbott

Lars Wallentin, MD
Professor of Cardiology
Uppsala University
Uppsala, Sweden

Grant/Research Support: AstraZeneca Pharmaceuticals LP, Boehringer Ingelheim Pharmaceuticals Inc., Bristol-Myers Squibb Company, GlaxoSmithKline, Schering-Plough Corporation

Jeffrey I. Weitz, MD, FRCP, FACP
Professor of Medicine and Biochemistry
McMaster University
Director, Henderson Research Center
Canada Research Chair in Thrombosis
Heart and Stroke Foundation
J.F. Mustard Chair in Cardiovascular Research
Ontario, Canada

Honoraria: Bristol-Myers Squibb, Daiichi-Sankyo, Takeda
Consultant: Boehringer-Ingelheim, sanofi-aventis, The Medicines Company, Bayer, Bristol-Myers Squibb, Eisai, Daiichi-Sankyo, Takeda

Salim Yusuf, MD
Professor of Medicine
Population Health Research Institute
McMaster University
Hamilton, Ontario

Grants/Research Support: sanofi-aventis and Bristol-Myers Squibb Company
Advisor or Consultant: sanofi-aventis and Bristol-Myers Squibb Company
Speaker or Speakers Bureau: sanofi-aventis and Bristol-Myers Squibb Company

Program Managers and Web Editor Disclosure Program Manager Gideon Bosker, MD has nothing to disclose.

Program Reviewers Denise Leary and Richard Aghababian, MD have nothing to disclose.

Educational Objectives

Upon completion of this activity, participants will:

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Content on this webcast is intended for educational value only. Its contents, analyses, and any recommendation made herein are intended to make scientific information and opinion available to health professionals, to stimulate thought, and further investigation. This webcast is not designed nor is any aspect of the contents here intended to provide advice regarding medical diagnosis or treatment for any individual case. Any decisions regarding diagnosis and/or management of any individual patient or group of patients should be made on individual basis after having consulted appropriate sources, whether they be appropriate consultants and/or guidelines and recommendations issued by national organizations, professional societies, governmental health organizations, or similar bodies. This webcast is not intended for use by the layman.

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iQ&A Interactive Medical Intelligence Zone for Stroke Prevention in AF