iQ&A Interactive Medical Intelligence Zone for Cancer and Thrombosis
iQ&A, The Interactive Medical Intelligence Zone is a needs assessment-driven continuing medical education (CME) activity that utilizes international experts to provide evidence-based, guideline-consistent, and practice behavior-changing information focused on critical and challenging topics in clinical medicine.
To ensure that the educational content of iQ&A programs will address practice gaps in clinical medicine, improve patient outcomes, and positively guide clinical practice strategies, international experts, usually in a roundtable format, will respond to questions submitted and/or generated by practitioners at CME mega-symposia, national congress, association meetings, or as part of on-line, enduring CME programs.
Questions reflecting the clinical needs of practitioners are then answered, analyzed, and discussed by international experts, who provide evidence-based and clinically relevant guidance that is independently of commercial sources or the program sponsor.
The iQ&A platform stresses:
  • Needs assessment-driven CME content
  • Evidence-based analysis
  • Expert-based guidance and consultation
  • Compliance adherence
  • Independence of content generation
  • Landmark trials
  • Association-generated practice management guidelines
  • Quality of care improvement
  • Practice gap improvement
Intended Audience

  • Oncology specialists
  • Surgical oncology specialists
  • VTE and thrombosis specialists
  • Hematology/oncology specialists
  • Hospital pharmacists
  • Anticoagulation specialists
  • Hospitalists
  • Oncology nurses and NPs


Enrollment for this iQandA interactive Medical Intelligence Zone is complimentary, and clinicians are invited to participate in this CME-certified program and/or share this invitation with other colleagues, departmental staff members, and healthcare professionals.

Grantor Support

Supported by an independent educational grant from Eisai, Inc.

Accreditation Statement

This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of The University of Massachusetts Medical School, Office of CME and CMEducation Resources, LLC. The University of Massachusetts Medical School is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation Statement

The University of Massachusetts Medical School designates this educational activity for a maximum of 3.0 AMA PRA Category 1 Credit(s). Physicians should only claim credit commensurate with the extent of their participation in the activity.

Policy on Faculty & Provider Disclosure

It is the policy of the Postgraduate Institute of Medicine to ensure fair balance, independence, objectivity and scientific rigor in all activities. All faculty participating in CME activities sponsored by the Postgraduate Institute of Medicine are required to present evidence-based data, identify and reference off-label product use and disclose all relevant financial relationships with those supporting the activity or others whose products or services are discussed. Faculty disclosure will be provided in the activity materials.

Program Faculty and Disclosure

Sam Schulman, MD
Chairman, Steering Committee/DSMB: Boehringer-Ingelheim, Bayer, AstraZeneca, sanofi-aventis, GlaxoSmithKline

Paul Ridker, MD
Consultant: AstraZeneca, Merck, Siemens, Isis
Grant/Researh Support: AstraZeneca, sanofi-aventis

Agnes Lee, MD
Consultant/Honoraria: Leo Pharma, Boehringer-Ingelheim, Bayer, Pfizer, sanofi-aventis
Grant/Research Support: Pfizer, Eisai

Clive Kearon, MD
Consultant: Boehringer-Ingelheim

Paul Stein, MD
Nothing to disclose

Craig Kessler, MD
Consultant: Eisai, sanofi-aventis
Grant/Research Support: Eisai, sanofi-aventis, GlaxoSmithKline
Stock Shareholder: Ibsen

Stavros Konstantinides, MD
Lecture fees: Bayer HealthCare, Bristol-Myers Squibb, Boehringer Ingelheim, CSL Behring, Daiichi Sankyo, GlaxoSmithKline, sanofi-aventis

Robert Handin, MD
Nothing to disclose

Elaine Hylek, MD
Advisory Boards: Bristol-Myers Squibb, sanofi-aventis, Boehringer-Ingelheim

Jeff Weitz, MD
Consultant: Bristol-Myers Squibb,Pfizer, Boehringer-Ingelheim, Bayer, sanofi-aventis

Prof. Paolo Prandoni, MD
Nothing to disclose

Ajay Kakkar, MD
Consultant: Pfizer, Bristol-Myers, Squibb, sanofi0aventis, Boehringer-Ingelnheim, Bayer, GlaxoSmithKline, Eisai, Aryx
Grant/Research Support: Pfizer, Bristol-Myers, Squibb, sanofi0aventis, Boehringer-Ingelnheim, Bayer, GlaxoSmithKline, Eisai, Aryx

Prof. Sylvia Haas
Consultant: Boehringer-Ingelheim
Speaker’s Bureau: Boehringer-Ingelheim, Bayer
Grant/Research Support: sanofi-aventis

H. R. Buller, MD
Consultant: Bayer, GlaxoSmithKline, sanofi-aventis, Daiichi Sankyo, Pfizer, Isis
Grant/Research Support: Bayer, GlaxoSmithKline, sanofi-aventis, Daiichi Sankyo, Pfizer, Isis

Dr. A.G.G. Turpie
Consultant: Bayer, Johnson & Johnson, Pfizer, Astellas
Speaker’s Bureau: GlaxoSmithKline, Bayer Canada

Benjamin Brenner, MD
Grant/Research Support: sanofi-aventis

Frederick Rickles, MD
Consultant: Eisai Pharmaceuticals, Genmab, Pharmacyclics
Speaker’s Bureau: Eisai Pharmaceuticals

Henri Bounameaux, MD
Consultant: Bayer-Schering, Pfizer, sanofi-aventis, Boehringer-Ingelheim, Canon Pharma
Grant/Research Support: Bayer-Schering, Schering-Plough

John Alexander, MD
Research Support: Bristol Myers Squibb, Medtronic Japan, NIH, Portola Pharma, Regado Biosciences, Medicure, Millennium Pharmaceuticals, Momenta Pharma, Schering Plough
Consulting / Honorarium: Adolor, Astra Zeneca, Daiichi Sankyo, Medicure, NIH, Novartis, Pfizer

Charles Francis, MD
Consultant: Boehringer-Ingelheim
Grant/Research Support: Eisai

Giancarlo Agnelli, MD
Consultant: sanofi-aventis, Bayer, Boehringer-Ingelheim

Edith Nutescu, PharmD, FCCP
Consultant: Baxter
Speaker’s Bureau: Eisai
Grant/Research Support: Ortho McNeill Johnson

Michael Streiff, MD
Speaker’s Bureau: sanofi-aventis
Grant/Research Support: Bristol-Myers Squibb
Honoraria: sanofi-aventis, GlaxoSmithKline

Samuel Z. Goldhaber, MD
Grant/Research Support: AstraZeneca; Boehringer-Ingelheim; Eisai; GSK; sanofi-aventis;
Consultant: Boehringer-Ingelheim; BMS; Eisai; Merck; Pfizer; sanofi-aventis

Sunil Rao, MD
Consultant: sanofi-aventis, The Medicines Company, Cordis Corporation
Research funding: Cordis Corporation, Momenta Pharmaceuticals, Portola Pharmaceuticals

Richard Becker, MD
Grant/Research Support: Johnson & Johnson, Bristol-Myers Squibb, Bayer, Merck, Regado Biosciences

Deepak Bhatt, MD
Consultant: Arena, Astra Zeneca, Bristol-Myers Squibb, Cardax, Cogentus, Daiichi Sankyo, Eli Lilly, Eisai, Glaxo Smith Kline, Johnson & Johnson, Medtronic, Millennium, Otsuka, Paringenix, PDL, Philips, Portola, sanofi-aventis, Schering Plough, Takeda, The Medicines Company, Vertex.
Principal Investigator for several potentially related studies. His institution has received funding from Bristol Myers Squibb, Eisai, Ethicon, Heartscape, sanofi-aventis, The Medicines Company.

William Geerts, MD
Consultant: Bayer, Boehringer-Ingelheim, Covidren
Honoraria: Bayer, Boehringer-Ingelheim, Pfizer, sanofi-aventis

Grants for educational activities and served as an advisor to GlaxoSmithKline, Medtronic, CV Therapeutics, The Medicines Company, sanofiaventis, Abbott, Boehringer Ingelheim, Pfizer and Eli Lilly and Company Grants for clinical research from Merck, Siemens, and Boston Scientific

Marco Valgimigli, MD, PhD
Senior Cardiologist
Department of Cardiology
University of Ferrara
Ferrara, Italy

Grants for clinical research from Merck.
Advisor or consultant for Medicines Company

Educational Objectives

Participants in this CME-certified iQandA will learn:
  • Apply NCCN, ASCO, and ACCP guidelines aimed at preventing primary and recurrent VTE in patients with cancer.
  • Assess patients with cancer, both in the inpatient and outpatient setting, and their likelihood for sustaining an initial or recurrent VTE; and, what the implications of their risk score is for prophylaxis management.
  • Compare the safety, efficacy, costs of monitoring, and long-term outcomes of vitamin K antagonists versus LMWHs when managing cancer patients who require secondary prevention of VTE.
  • Apply the results of landmark clinical trials in cancer and thrombosis to the front lines of oncology and surgical oncology care.
  • Explain the mechanisms of thrombosis formation in cancer and the effects of LWMHs on inhibition of the coagulation cascade and on angiogenesis.


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