iQ&A Interactive Medical Intelligence Zone for Pharmacoresisant Seizures
The Interactive Medical Intelligence Zone is a needs assessment-driven continuing medical education (CME) activity that utilizes national and international experts to provide evidence-based, guideline-consistent, and practice behavior-changing information focused on critical and challenging topics in clinical medicine.
To ensure that the educational content of iQ&A programs will address practice gaps in clinical medicine, improve patient outcomes, and positively guide clinical practice strategies, international experts, usually in a roundtable format, will respond to questions submitted and/or generated by practitioners at CME mega-symposia, national congress, association meetings, or as part of on-line, enduring CME programs.
Questions reflecting the clinical needs of practitioners are then answered, analyzed, and discussed by international experts, who provide evidence-based and clinically relevant guidance that is independently of commercial sources or the program sponsor.
The iQ&A platform stresses:
  • Needs assessment-driven CME content
  • Evidence-based analysis
  • Expert-based guidance and consultation
  • Compliance adherence
  • Independence of content generation
  • Landmark trials
  • Association-generated practice management guidelines
  • Quality of care improvement
  • Practice gap improvement

Program Medium
Internet-based program

Method of Physician Participation Utilized in Learning Process

There are no fees for participating and receiving CME credit for this activity. During the period September 16, 2013 through September 16, 2015, participants must 1) read the learning objectives and faculty disclosures; 2) study the educational activity, and are expected to view all 45 segments, totaling 2 hours, to successfully complete the activity and earn CME credit; 3) register and complete the evaluation form and post-test; 4) score 100% on the post-test; and 5) print out CME certificate.

2.0 hours. Physicians must study the enduring activity, and are expected to view every segment to successfully complete the activity and earn CME credit.

Course Overview

In this web-based program, physicians will learn how recent advances in basic and clinical research have helped to advance the understanding of treatment advances in the management of partial-onset seizures.

Release Date

September 16, 2013

Expiration Date

September 16, 2015

Intended Audience

This complimentary CME educational activity is designed for all healthcare providers (HCPs) involved in developing, delivering, consulting, and monitoring care for patients with partial-onset seizures.

This constituency of HCPs shall include the following audience:

  • Neurologists
  • Pediatric neurologists
  • Epilepsy specialists
  • Neuropharmacologists


Participation in this iQ&A interactive Medical Intelligence Zone for Partial-Onset Seizures is complimentary, and clinicians are invited to view this CME-certified program and/or share this invitation with other colleagues, departmental staff members, and healthcare professionals.

Grantor Support

Supported by an educational grant from Eisai, Inc.

Eisai, Inc.e

Accreditation Statement

This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of Complete Conference Management and CMEducation Resources, LLC. Complete Conference Management is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation Statement

Complete Conference Management designates this enduring material for a maximum of 2.0 AMA PRA Category 1 Credits(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Policy on Faculty & Provider Disclosure

It is the policy of Complete Conference Management to ensure fair balance, independence, objectivity and scientific rigor in all activities. All faculty participating in CME activities sponsored by Complete Conference Management are required to present evidence-based data, identify and reference off-label product use and disclose all relevant financial relationships with those supporting the activity or others whose products or services are discussed. Faculty disclosure will be provided in the activity materials.

Policy on Faculty & Provider Disclosure

It is the policy of Complete Conference Management to ensure fair balance, independence, objectivity and scientific rigor in all activities. All faculty participating in CME activities sponsored by Complete Conference Management are required to present evidence-based data, identify and reference off-label product use and disclose all relevant financial relationships with those supporting the activity or others whose products or services are discussed. Faculty disclosure will be provided in the activity materials.

Program Faculty and Disclosure

Michael D. Privitera, MD
Professor of Neurology
University of Cincinnati
Director, Epilepsy Center
UC Neuroscience Center
Cincinnati, OH

Consultant: Upsher Smith
DSMB Committee: Lilly
Grant/Research Support: UCB, Eisai

Michael A. Rogawski, MD, PhD
Department of Neurology
University of California Davis School of Medicine
UC Davis Center for Neuroscience
Davis, California

Grant/Research Support: Eisai
Speaker: Eisai
Advisory Board: Eisai

Barry E. Gidal, PharmD, RPh
Professor of Pharmacy and Neurology
University of Wisconsin
Madison, WI

Speaker Honoraria: UCB, GlaxoSmithKline
Consultant: UCB, Eisai, USL

Andrew N. Wilner, MD
Lawrence & Memorial Hospital
New London, Connecticut

Advisor: Accordant Health Services
Stock: Pfizer, GlaxoSmithKline
Publication Royalties: Demos Publications

James W. Wheless, MD
Adjunct Faculty, St. Jude Children’s Research Hospital
Professor and Chief of Pediatric Neurology
University of Tennessee Health Science Center
Le Bonheur Chair in Pediatric Neurology
Director, Le Bonheur Comprehensive Epilepsy Program
Director, Neuroscience Institute
Le Bonheur Children's Medical Center
Memphis, Tennessee

Consultant: Lundbeck Research USA, Inc.; Questcor Pharmaceuticals, Inc.; Cyberonics, Inc.; Pfizer Inc.; Eisai Inc.; Sunovian Pharmaceuticals, Inc.; Novartis Pharmaceuticals Corporation
Speaker: GlaxoSmithKline; Lundbeck Research USA, Inc.; Questcor Pharmaceuticals, Inc.; Cyberonics, Inc.; Eisai Inc.; UCB Pharma, Inc.; Novartis Pharmaceuticals Corporation
Grant/Research Support: National Institute of Health; Shainberg Foundation; GlaxoSmithKline; Lundbeck Research USA, Inc.; King Pharmaceuticals Inc.; Eisai Inc.; Supernus Pharmaceuticals, Inc.

Gregory Krauss, MD
Professor of Neurology
Johns Hopkins School of Medicine Epilepsy Center
Baltimore, Maryland

Consultant: Eisai
Grant/Research Support: Eisai, Vertex, Sunovion, SK Bio

John M. Pellock, MD
Chairman, Division of Child Neurology
Professor of Neurology, Pediatrics and Pharmacy and Pharmaceutics Virginia Commonwealth University
Medical College of Virginia
Richmond, Virginia

Consultant: Catalyst Pharmaceutical Partners; Inc.; Eisai Inc.; GlaxoSmithKline; King Pharmaceuticals Inc.; KV Pharmaceutical Company; Marinus Pharmaceuticals, Inc.; NeuroPace, Inc.; Lundbeck, Inc.; Pfizer Inc; Questcor Pharmaceuticals, Inc.; Sepracor Inc.; Sunovion Pharmaceuticals Inc.; UCB Pharma, Inc.; Upshur-Smith Laboratories, Inc.; Valeant Pharmaceuticals International
Grant/Research Support: Eisai Inc.; Marinus Pharmaceuticals, Inc.; Lundbeck, Inc.; Pfizer Inc; Questcor Pharmaceuticals, Inc.; UCB Pharma, Inc.; Upshur-Smith Laboratories International

Timothy E. Welty, PharmD FCCP BCPS
Professor and Chair
Department of Clinical Sciences
College of Pharmacy and Health Sciences
Drake University
Des Moines, IA

Nothing to disclose


Program Managers and Web Editor Disclosure

Program Manager Gideon Bosker, MD has nothing to disclose.

Educational Objectives

Upon completion of this activity, participants will be able to:

  • Detail the mechanisms of action, novel targets, and the use of combination AED-based strategies for POS that are supported by evidence, clinical trials, and guidelines for managing refractory seizures in the setting of POS;
  • Describe epidemiology, medical burden, and natural history of partial onset seizures (POS) with a focus on clinical dilemmas, refractory seizures, pharmacoresistance, and new therapeutic paradigms to optimize seizure freedom in patients with POS;
  • Describe the role and potential clinical usefulness of neuroreceptors and synaptic targets involved in neuronal excitation, including the role of potassium channel agonists, voltage-dependent sodium channels, and intracellular calcium fluxes in triggering or sustaining seizure activity;
  • Manage case studies in POS and refractory seizures, becoming more clinically proficient in sequencing, switching, and/or combining established, traditional AEDs with agents that produce therapeutic effects through novel mechanisms;
  • Apply the results and findings from landmark clinical and therapeutic trials in POS, including the role of so-called “third generation” agents that effect novel targets and, therefore, can be used as adjunctive therapy in patients with POS and refractory seizures;
Hardware and Software Requirements:

To participate in this program, viewers must have a PC or Macintosh computer that has active, ongoing internet access for the duration of the program, as well as a compatible Flash-viewer. An email address is required for registration, and a printer is required to print out the CME certificate.

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When you participate in a CME activity offered by CMEducation Resources, we ask you for your name, degree, affiliation, street address, telephone number, fax number, and/or e-mail address (the "Information"). We use that Information in the following ways:

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Copyright © 2013 by CMEducation Resources, LLC All rights reserved. 

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